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Questões do ENEM: Linguagens

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Página 409 de 950

  • Linguagens

    Inglês

    Examine o quadrinho para responder a questão. 


    The Joy of Tech                                     by Nitrozac & Snaggy

    Imagem da questão de Inglês, UNIFESP 2014, Interpretação de texto | Reading comprehension
                                                                                                       (www.starling-fitness.com)
    O quadrinho faz uma crítica
    Escolha uma alternativa para a questão 6cb598d3-b1
  • Linguagens

    Português

    Leia o texto a seguir e responda à questão.


        Na linguagem cotidiana a palavra trabalho tem muitos significados. Embora pareça compreensível, como uma das formas elementares de ação dos homens, o seu conteúdo oscila. Às vezes, carregada de emoção, lembra dor, tortura, suor do rosto, fadiga. Noutras, mais que aflição e fardo, designa a operação humana de transformação da matéria natural em objeto de cultura. É o homem em ação para sobreviver e realizar-se, criando instrumentos, e com esses, todo um novo universo cujas vinculações com a natureza, embora inegáveis, se tornam opacas.
        Em quase todas as línguas da cultura europeia, trabalhar tem mais de uma significação. (...) Em português, apesar de haver labor e trabalho, é possível achar na mesma palavra trabalho ambas as significações: a de realizar uma obra que expresse o indivíduo, que lhe dê reconhecimento social e permaneça além de sua vida; e a de esforço rotineiro e repetitivo, sem liberdade, de resultado consumível e incômodo inevitável.
        No dicionário aparece em primeiro lugar o significado de aplicação das forças e faculdades humanas para alcançar determinado fim; atividade coordenada de caráter físico ou intelectual, necessária a qualquer tarefa, serviço ou empreendimento; exercício dessa atividade como ocupação permanente, ofício, profissão.
        Mas trabalho tem outros significados mais particulares, como o de esforço aplicado à produção de utilidades ou obras de arte, mesmo dissertação ou discurso. Pode significar o conjunto das discussões e deliberações de uma sociedade ou assembleia convocada para tratar de interesse público, coletivo ou particular: “Os trabalhos da assembleia do sindicato tiveram como resultado a greve”. Pode significar o serviço de uma repartição burocrática, e ainda os deveres escolares dos alunos a serem verificados pelos professores. Como pode indicar o processo do nascimento da criança: “a mulher entrou em trabalho de parto”.
        Além de atividade e exercício, trabalho também significa dificuldade e incômodo: “aqui vieram passar trabalho”; “a última enchente deu muito trabalho”. Pois junto a todas as suas significações ativas, trabalho em português, e no plural, quer dizer preocupações, desgostos e aflições. É o conteúdo que predomina em labor, mas ainda está presente em trabalho.
        Isso se compreende melhor ao descobrir que em nossa língua a palavra trabalho se origina do latim tripalium, embora outras hipóteses a associem a trabaculum. Tripalium era um instrumento feito de três paus aguçados, algumas vezes ainda munidos de pontas de ferro, usado pelos agricultores para bater o trigo, as espigas de milho, o linho, para rasgá-los e esfiapá-los. A maioria dos dicionários, contudo, registra tripalium apenas como instrumento de tortura, o que teria sido originalmente, ou se tornado depois. A tripalium se liga o verbo do latim vulgar tripaliare, que significa justamente torturar.
        Ainda que originalmente o tripalium fosse usado no trabalho do agricultor, no trato do cereal, é do uso desse instrumento como meio de tortura que a palavra trabalho significou por muito tempo – e ainda conota – algo como padecimento e cativeiro. Desse conteúdo semântico de sofrer passou-se ao de esforçar-se, laborar e obrar. O primeiro sentido teria perdurado até o início do século XV; essa evolução de sentido teria ocorrido ao mesmo tempo em outras línguas latinas, como trabajo em espanhol, traballo em catalão, travail em francês e travaglio em italiano.
        No dicionário filosófico você poderá encontrar que o homem trabalha quando põe em atividade suas forças espirituais ou corporais, tendo em mira um fim sério que deve ser realizado ou alcançado. Assim, mesmo que não se produza nada imediatamente visível com o esforço do estudo, o trabalho de ordem intelectual corresponde àquela definição tanto quanto o trabalho corporal, embora seja este que leve a um resultado exteriormente perceptível, a um produto concreto ou a uma mudança de estado ou situação.
        Todo trabalho supõe tendência para um fim e esforço. Para alguns trabalhos, esse esforço será preponderantemente físico; para outros, preponderantemente intelectual. Contudo, parece míope e interesseira essa classificação que divide trabalho intelectual e trabalho corporal. A maioria dos esforços intelectuais se faz acompanhar de esforço corporal; uso minhas mãos e os músculos do braço quando datilografo estas páginas, que vou pensando. E o pedreiro usa sua inteligência ao empilhar com equilíbrio os tijolos sobre o cimento ainda não solidificado.
        O trabalho do homem aparece cada vez mais nítido quanto mais clara for a intenção e a direção de seu esforço. Trabalho, nesse sentido, possui o significado ativo de um esforço afirmado e desejado para a realização de objetivos; até mesmo o objetivo realizado, a obra, passa a ser chamado trabalho. Trabalho é o esforço e também seu resultado: a construção como processo e ação, e o edifício pronto. (Suzana Albornoz. Texto adaptado).
    Assinale a alternativa que indica adequadamente um título para o texto de Suzana Albornoz, tomando por base o aproveitamento de suas principais ideias.
    Escolha uma alternativa para a questão 6cb6b570-eb
  • Linguagens

    Inglês

    Which recipe is an example of a vegan dish?

    Escolha uma alternativa para a questão 6cb8bf46-ff
  • Linguagens

    Português

    Imagem da questão de Português, UNESP 2013, Coesão e coerência Como estudos ainda não conseguiram decifrar como direcionar a criatividade de uma maneira que certamente despertará esse interesse (e maximizará a produção), a opção normalmente costuma ser pela solução mais simples.

    O período em destaque apresenta muitos ecos (coincidências de sons de finais de palavras). Uma das formas de evitá-los e tornar a sequência mais fluente seria colocar “conduzir”, “tal”, “quantidade produzida” em lugar de, respectivamente,
    Escolha uma alternativa para a questão 6cb9f873-9f
  • Linguagens

    Inglês

    Examine o quadrinho para responder a questão. 


    The Joy of Tech                                     by Nitrozac & Snaggy

    Imagem da questão de Inglês, UNIFESP 2014, Interpretação de texto | Reading comprehension
                                                                                                       (www.starling-fitness.com)
    When introduced to “real food” the children express
    Escolha uma alternativa para a questão 6cba0f30-b1
  • Linguagens

    Inglês

    After reading the strip below, you can conclude that the dog:


    Imagem da questão de Inglês, URCA 2017, Interpretação de texto | Reading comprehension
    Escolha uma alternativa para a questão 6cbc4d6d-ff
  • Linguagens

    Inglês

    Leia o texto para responder a questão.

    Healthy choices

    How do we reduce waistlines in a country where we traditionally do not like telling individuals what to do?

    By Telegraph View

    22 Aug 2014

                                                                                        Duncan Selbie, the Chief Executive of Public Health

                                                                                                      England, suggests that parents feed their children

                                                                                                      from smaller plates. Photo: Alamy


       Every new piece of information about Britain’s weight problem makes for ever more depressing reading. Duncan Selbie, the Chief Executive of Public Health England, today tells us that by 2034 some six million Britons will suffer from diabetes. Of course, many people develop diabetes through no fault of their own. But Mr Selbie’s research concludes that if the levels of obesity returned to their 1994 levels, 1.7 million fewer people would suffer from the condition.

      Given that fighting diabetes already drains the National Health Service (NHS) by more than £1.5 million, or 10 per cent of its budget for England, the impact upon the Treasury in 20 years’ time from unhealthy lifestyles could be catastrophic. Bad health not only impacts on the individual but also on the rest of the community.

       Diagnosis of the challenge is straightforward. The tougher question is what to do about reducing waistlines in a country where we traditionally do not like telling individuals what to do.

       It is interesting to note that Mr Selbie does not ascribe to the Big Brother approach of ceaseless legislation and nannying. Rather, he is keen to promote choices – making the case passionately that people should be encouraged to embrace good health. One of his suggestions is that parents feed their children from smaller plates. That way the child can clear his or her plate, as ordered, without actually consuming too much. Like all good ideas, this is rooted in common sense. 

    (www.telegraph.co.uk. Adaptado.)

    According to the text, Mr Duncan Selbie concluded that
    Escolha uma alternativa para a questão 6cbd2e58-b1
  • Linguagens

    Inglês

    Leia o texto para responder a questão.

    Healthy choices

    How do we reduce waistlines in a country where we traditionally do not like telling individuals what to do?

    By Telegraph View

    22 Aug 2014

                                                                                        Duncan Selbie, the Chief Executive of Public Health

                                                                                                      England, suggests that parents feed their children

                                                                                                      from smaller plates. Photo: Alamy


       Every new piece of information about Britain’s weight problem makes for ever more depressing reading. Duncan Selbie, the Chief Executive of Public Health England, today tells us that by 2034 some six million Britons will suffer from diabetes. Of course, many people develop diabetes through no fault of their own. But Mr Selbie’s research concludes that if the levels of obesity returned to their 1994 levels, 1.7 million fewer people would suffer from the condition.

      Given that fighting diabetes already drains the National Health Service (NHS) by more than £1.5 million, or 10 per cent of its budget for England, the impact upon the Treasury in 20 years’ time from unhealthy lifestyles could be catastrophic. Bad health not only impacts on the individual but also on the rest of the community.

       Diagnosis of the challenge is straightforward. The tougher question is what to do about reducing waistlines in a country where we traditionally do not like telling individuals what to do.

       It is interesting to note that Mr Selbie does not ascribe to the Big Brother approach of ceaseless legislation and nannying. Rather, he is keen to promote choices – making the case passionately that people should be encouraged to embrace good health. One of his suggestions is that parents feed their children from smaller plates. That way the child can clear his or her plate, as ordered, without actually consuming too much. Like all good ideas, this is rooted in common sense. 

    (www.telegraph.co.uk. Adaptado.)

    The excerpt from the first paragraph “many people develop diabetes through no fault of their own” means that these people
    Escolha uma alternativa para a questão 6cc05fa1-b1
  • Linguagens

    Inglês

    Leia o texto para responder a questão.

    Healthy choices

    How do we reduce waistlines in a country where we traditionally do not like telling individuals what to do?

    By Telegraph View

    22 Aug 2014

                                                                                        Duncan Selbie, the Chief Executive of Public Health

                                                                                                      England, suggests that parents feed their children

                                                                                                      from smaller plates. Photo: Alamy


       Every new piece of information about Britain’s weight problem makes for ever more depressing reading. Duncan Selbie, the Chief Executive of Public Health England, today tells us that by 2034 some six million Britons will suffer from diabetes. Of course, many people develop diabetes through no fault of their own. But Mr Selbie’s research concludes that if the levels of obesity returned to their 1994 levels, 1.7 million fewer people would suffer from the condition.

      Given that fighting diabetes already drains the National Health Service (NHS) by more than £1.5 million, or 10 per cent of its budget for England, the impact upon the Treasury in 20 years’ time from unhealthy lifestyles could be catastrophic. Bad health not only impacts on the individual but also on the rest of the community.

       Diagnosis of the challenge is straightforward. The tougher question is what to do about reducing waistlines in a country where we traditionally do not like telling individuals what to do.

       It is interesting to note that Mr Selbie does not ascribe to the Big Brother approach of ceaseless legislation and nannying. Rather, he is keen to promote choices – making the case passionately that people should be encouraged to embrace good health. One of his suggestions is that parents feed their children from smaller plates. That way the child can clear his or her plate, as ordered, without actually consuming too much. Like all good ideas, this is rooted in common sense. 

    (www.telegraph.co.uk. Adaptado.)

    Segundo o texto, a diabetes
    Escolha uma alternativa para a questão 6cc45b8b-b1
  • Linguagens

    Inglês

    Leia o texto para responder a questão.

    Healthy choices

    How do we reduce waistlines in a country where we traditionally do not like telling individuals what to do?

    By Telegraph View

    22 Aug 2014

                                                                                        Duncan Selbie, the Chief Executive of Public Health

                                                                                                      England, suggests that parents feed their children

                                                                                                      from smaller plates. Photo: Alamy


       Every new piece of information about Britain’s weight problem makes for ever more depressing reading. Duncan Selbie, the Chief Executive of Public Health England, today tells us that by 2034 some six million Britons will suffer from diabetes. Of course, many people develop diabetes through no fault of their own. But Mr Selbie’s research concludes that if the levels of obesity returned to their 1994 levels, 1.7 million fewer people would suffer from the condition.

      Given that fighting diabetes already drains the National Health Service (NHS) by more than £1.5 million, or 10 per cent of its budget for England, the impact upon the Treasury in 20 years’ time from unhealthy lifestyles could be catastrophic. Bad health not only impacts on the individual but also on the rest of the community.

       Diagnosis of the challenge is straightforward. The tougher question is what to do about reducing waistlines in a country where we traditionally do not like telling individuals what to do.

       It is interesting to note that Mr Selbie does not ascribe to the Big Brother approach of ceaseless legislation and nannying. Rather, he is keen to promote choices – making the case passionately that people should be encouraged to embrace good health. One of his suggestions is that parents feed their children from smaller plates. That way the child can clear his or her plate, as ordered, without actually consuming too much. Like all good ideas, this is rooted in common sense. 

    (www.telegraph.co.uk. Adaptado.)

    No trecho inicial do segundo parágrafo “Given that fighting diabetes already drains the National Health Service”, a expressão em destaque introduz
    Escolha uma alternativa para a questão 6cc851ce-b1
  • Linguagens

    Inglês

    Leia o texto para responder a questão.

    Healthy choices

    How do we reduce waistlines in a country where we traditionally do not like telling individuals what to do?

    By Telegraph View

    22 Aug 2014

                                                                                        Duncan Selbie, the Chief Executive of Public Health

                                                                                                      England, suggests that parents feed their children

                                                                                                      from smaller plates. Photo: Alamy


       Every new piece of information about Britain’s weight problem makes for ever more depressing reading. Duncan Selbie, the Chief Executive of Public Health England, today tells us that by 2034 some six million Britons will suffer from diabetes. Of course, many people develop diabetes through no fault of their own. But Mr Selbie’s research concludes that if the levels of obesity returned to their 1994 levels, 1.7 million fewer people would suffer from the condition.

      Given that fighting diabetes already drains the National Health Service (NHS) by more than £1.5 million, or 10 per cent of its budget for England, the impact upon the Treasury in 20 years’ time from unhealthy lifestyles could be catastrophic. Bad health not only impacts on the individual but also on the rest of the community.

       Diagnosis of the challenge is straightforward. The tougher question is what to do about reducing waistlines in a country where we traditionally do not like telling individuals what to do.

       It is interesting to note that Mr Selbie does not ascribe to the Big Brother approach of ceaseless legislation and nannying. Rather, he is keen to promote choices – making the case passionately that people should be encouraged to embrace good health. One of his suggestions is that parents feed their children from smaller plates. That way the child can clear his or her plate, as ordered, without actually consuming too much. Like all good ideas, this is rooted in common sense. 

    (www.telegraph.co.uk. Adaptado.)

    No trecho do segundo parágrafo “Bad health not only impacts on the individual but also on the rest of the community”, a expressão “not only … but also” indica uma ideia de
    Escolha uma alternativa para a questão 6ccd11cf-b1
  • Linguagens

    Português

    Leia os Textos 4 e 5 para responder às questões de 08 a 10.

    Figura 1 de 2 da questão de Português, UFG 2010, Interpretação de Textos

    Figura 2 de 2 da questão de Português, UFG 2010, Interpretação de Textos

    O slogan de Getúlio Vargas é escrito no tempo verbal futuro. Tendo em vista os interesses do candidato, que efeito de sentido esse uso ajuda a produzir?
    Escolha uma alternativa para a questão 6ccd44e6-58
  • Linguagens

    Português

    Sobre Crepúsculo dos deuses, de Billy Wilder, é correto afirmar que:
    Escolha uma alternativa para a questão 6cce2a64-eb
  • Linguagens

    Inglês

    Leia o texto para responder a questão.

    Healthy choices

    How do we reduce waistlines in a country where we traditionally do not like telling individuals what to do?

    By Telegraph View

    22 Aug 2014

                                                                                        Duncan Selbie, the Chief Executive of Public Health

                                                                                                      England, suggests that parents feed their children

                                                                                                      from smaller plates. Photo: Alamy


       Every new piece of information about Britain’s weight problem makes for ever more depressing reading. Duncan Selbie, the Chief Executive of Public Health England, today tells us that by 2034 some six million Britons will suffer from diabetes. Of course, many people develop diabetes through no fault of their own. But Mr Selbie’s research concludes that if the levels of obesity returned to their 1994 levels, 1.7 million fewer people would suffer from the condition.

      Given that fighting diabetes already drains the National Health Service (NHS) by more than £1.5 million, or 10 per cent of its budget for England, the impact upon the Treasury in 20 years’ time from unhealthy lifestyles could be catastrophic. Bad health not only impacts on the individual but also on the rest of the community.

       Diagnosis of the challenge is straightforward. The tougher question is what to do about reducing waistlines in a country where we traditionally do not like telling individuals what to do.

       It is interesting to note that Mr Selbie does not ascribe to the Big Brother approach of ceaseless legislation and nannying. Rather, he is keen to promote choices – making the case passionately that people should be encouraged to embrace good health. One of his suggestions is that parents feed their children from smaller plates. That way the child can clear his or her plate, as ordered, without actually consuming too much. Like all good ideas, this is rooted in common sense. 

    (www.telegraph.co.uk. Adaptado.)

    No trecho do quarto parágrafo “Rather, he is keen to promote choices”, o termo em destaque equivale, em português, a
    Escolha uma alternativa para a questão 6cd00db0-b1
  • Linguagens

    Português

    Assinale a alternativa correta sobre Edifício Master, de Eduardo Coutinho.
    Escolha uma alternativa para a questão 6cd14c99-eb
  • Linguagens

    Inglês

    Leia o texto para responder a questão.


    The Rise of Antibiotic Resistance 

    By The Editorial Board

    May 10, 2014


        The World Health Organization has surveyed the growth of antibiotic-resistant germs around the world – the first such survey it has ever conducted – and come up with disturbing findings. In a report issued late last month, the organization found that antimicrobial resistance in bacteria (the main focus of the report), fungi, viruses and parasites is an increasingly serious threat in every part of the world. “A problem so serious that it threatens the achievements of modern medicine,” the organization said. “A post-antibiotic era, in which common infections and minor injuries can kill, far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.” 

        The growth of antibiotic-resistant pathogens means that in ever more cases, standard treatments no longer work, infections are harder or impossible to control, the risk of spreading infections to others is increased, and illnesses and hospital stays are prolonged. All of these drive up the costs of illnesses and the risk of death. The survey sought to determine the scope of the problem by asking countries to submit their most recent surveillance data (114 did so). Unfortunately, the data was glaringly incomplete because few countries track and monitor antibiotic resistance comprehensively, and there is no standard methodology for doing so.

        Still, it is clear that major resistance problems have already developed, both for antibiotics that are used routinely and for those deemed “last resort” treatments to cure people when all else has failed. Carbapenem antibiotics, a class of drugs used as a last resort to treat life-threatening infections caused by a common intestinal bacterium, have failed to work in more than half the people treated in some countries. The bacterium is a major cause of hospital-acquired infections such as pneumonia, bloodstream infections, and infections in newborns and intensive-care patients. Similarly, the failure of a last-resort treatment for gonorrhoea has been confirmed in 10 countries, including many with advanced health care systems, such as Australia, Canada, France, Sweden and Britain. And resistance to a class of antibiotics that is routinely used to treat urinary tract infections caused by E. coli is widespread; in some countries the drugs are now ineffective in more than half of the patients treated. This sobering report is intended to kick-start a global campaign to develop tools and standards to track drug resistance, measure its health and economic impact, and design solutions.

       The most urgent need is to minimize the overuse of antibiotics in medicine and agriculture, which accelerates the development of resistant strains. In the United States, the Food and Drug Administration (FDA) has issued voluntary guidelines calling on drug companies, animal producers and veterinarians to stop indiscriminately using antibiotics that are important for treating humans on livestock; the drug companies have said they will comply. But the agency, shortsightedly, has appealed a court order requiring it to ban the use of penicillin and two forms of tetracycline by animal producers to promote growth unless they provide proof that it will not promote drug-resistant microbes.

       The pharmaceutical industry needs to be encouraged to develop new antibiotics to supplement those that are losing their effectiveness. The Royal Pharmaceutical Society, which represents pharmacists in Britain, called this month for stronger financial incentives. It said that no new class of antibiotics has been discovered since 1987, largely because the financial returns for finding new classes of antibiotics are too low. Unlike lucrative drugs to treat chronic diseases like cancer and cardiovascular ailments, antibiotics are typically taken for a short period of time, and any new drug is apt to be used sparingly and held in reserve to treat patients resistant to existing drugs. Antibiotics have transformed medicine and saved countless lives over the past seven decades. Now, rampant overuse and the lack of new drugs in the pipeline threaten to undermine their effectiveness.

    (www.nytimes.com. Adaptado.)

    Segundo o texto, um dos objetivos do relatório da Organização Mundial da Saúde é
    Escolha uma alternativa para a questão 6cd3ef3d-b1
  • Linguagens

    Inglês

    Leia o texto para responder a questão.


    The Rise of Antibiotic Resistance 

    By The Editorial Board

    May 10, 2014


        The World Health Organization has surveyed the growth of antibiotic-resistant germs around the world – the first such survey it has ever conducted – and come up with disturbing findings. In a report issued late last month, the organization found that antimicrobial resistance in bacteria (the main focus of the report), fungi, viruses and parasites is an increasingly serious threat in every part of the world. “A problem so serious that it threatens the achievements of modern medicine,” the organization said. “A post-antibiotic era, in which common infections and minor injuries can kill, far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.” 

        The growth of antibiotic-resistant pathogens means that in ever more cases, standard treatments no longer work, infections are harder or impossible to control, the risk of spreading infections to others is increased, and illnesses and hospital stays are prolonged. All of these drive up the costs of illnesses and the risk of death. The survey sought to determine the scope of the problem by asking countries to submit their most recent surveillance data (114 did so). Unfortunately, the data was glaringly incomplete because few countries track and monitor antibiotic resistance comprehensively, and there is no standard methodology for doing so.

        Still, it is clear that major resistance problems have already developed, both for antibiotics that are used routinely and for those deemed “last resort” treatments to cure people when all else has failed. Carbapenem antibiotics, a class of drugs used as a last resort to treat life-threatening infections caused by a common intestinal bacterium, have failed to work in more than half the people treated in some countries. The bacterium is a major cause of hospital-acquired infections such as pneumonia, bloodstream infections, and infections in newborns and intensive-care patients. Similarly, the failure of a last-resort treatment for gonorrhoea has been confirmed in 10 countries, including many with advanced health care systems, such as Australia, Canada, France, Sweden and Britain. And resistance to a class of antibiotics that is routinely used to treat urinary tract infections caused by E. coli is widespread; in some countries the drugs are now ineffective in more than half of the patients treated. This sobering report is intended to kick-start a global campaign to develop tools and standards to track drug resistance, measure its health and economic impact, and design solutions.

       The most urgent need is to minimize the overuse of antibiotics in medicine and agriculture, which accelerates the development of resistant strains. In the United States, the Food and Drug Administration (FDA) has issued voluntary guidelines calling on drug companies, animal producers and veterinarians to stop indiscriminately using antibiotics that are important for treating humans on livestock; the drug companies have said they will comply. But the agency, shortsightedly, has appealed a court order requiring it to ban the use of penicillin and two forms of tetracycline by animal producers to promote growth unless they provide proof that it will not promote drug-resistant microbes.

       The pharmaceutical industry needs to be encouraged to develop new antibiotics to supplement those that are losing their effectiveness. The Royal Pharmaceutical Society, which represents pharmacists in Britain, called this month for stronger financial incentives. It said that no new class of antibiotics has been discovered since 1987, largely because the financial returns for finding new classes of antibiotics are too low. Unlike lucrative drugs to treat chronic diseases like cancer and cardiovascular ailments, antibiotics are typically taken for a short period of time, and any new drug is apt to be used sparingly and held in reserve to treat patients resistant to existing drugs. Antibiotics have transformed medicine and saved countless lives over the past seven decades. Now, rampant overuse and the lack of new drugs in the pipeline threaten to undermine their effectiveness.

    (www.nytimes.com. Adaptado.)

    Segundo o texto, o relatório da Organização Mundial da Saúde
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    The Rise of Antibiotic Resistance 

    By The Editorial Board

    May 10, 2014


        The World Health Organization has surveyed the growth of antibiotic-resistant germs around the world – the first such survey it has ever conducted – and come up with disturbing findings. In a report issued late last month, the organization found that antimicrobial resistance in bacteria (the main focus of the report), fungi, viruses and parasites is an increasingly serious threat in every part of the world. “A problem so serious that it threatens the achievements of modern medicine,” the organization said. “A post-antibiotic era, in which common infections and minor injuries can kill, far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.” 

        The growth of antibiotic-resistant pathogens means that in ever more cases, standard treatments no longer work, infections are harder or impossible to control, the risk of spreading infections to others is increased, and illnesses and hospital stays are prolonged. All of these drive up the costs of illnesses and the risk of death. The survey sought to determine the scope of the problem by asking countries to submit their most recent surveillance data (114 did so). Unfortunately, the data was glaringly incomplete because few countries track and monitor antibiotic resistance comprehensively, and there is no standard methodology for doing so.

        Still, it is clear that major resistance problems have already developed, both for antibiotics that are used routinely and for those deemed “last resort” treatments to cure people when all else has failed. Carbapenem antibiotics, a class of drugs used as a last resort to treat life-threatening infections caused by a common intestinal bacterium, have failed to work in more than half the people treated in some countries. The bacterium is a major cause of hospital-acquired infections such as pneumonia, bloodstream infections, and infections in newborns and intensive-care patients. Similarly, the failure of a last-resort treatment for gonorrhoea has been confirmed in 10 countries, including many with advanced health care systems, such as Australia, Canada, France, Sweden and Britain. And resistance to a class of antibiotics that is routinely used to treat urinary tract infections caused by E. coli is widespread; in some countries the drugs are now ineffective in more than half of the patients treated. This sobering report is intended to kick-start a global campaign to develop tools and standards to track drug resistance, measure its health and economic impact, and design solutions.

       The most urgent need is to minimize the overuse of antibiotics in medicine and agriculture, which accelerates the development of resistant strains. In the United States, the Food and Drug Administration (FDA) has issued voluntary guidelines calling on drug companies, animal producers and veterinarians to stop indiscriminately using antibiotics that are important for treating humans on livestock; the drug companies have said they will comply. But the agency, shortsightedly, has appealed a court order requiring it to ban the use of penicillin and two forms of tetracycline by animal producers to promote growth unless they provide proof that it will not promote drug-resistant microbes.

       The pharmaceutical industry needs to be encouraged to develop new antibiotics to supplement those that are losing their effectiveness. The Royal Pharmaceutical Society, which represents pharmacists in Britain, called this month for stronger financial incentives. It said that no new class of antibiotics has been discovered since 1987, largely because the financial returns for finding new classes of antibiotics are too low. Unlike lucrative drugs to treat chronic diseases like cancer and cardiovascular ailments, antibiotics are typically taken for a short period of time, and any new drug is apt to be used sparingly and held in reserve to treat patients resistant to existing drugs. Antibiotics have transformed medicine and saved countless lives over the past seven decades. Now, rampant overuse and the lack of new drugs in the pipeline threaten to undermine their effectiveness.

    (www.nytimes.com. Adaptado.)

    According to the text, last resort antibiotics
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    The Rise of Antibiotic Resistance 

    By The Editorial Board

    May 10, 2014


        The World Health Organization has surveyed the growth of antibiotic-resistant germs around the world – the first such survey it has ever conducted – and come up with disturbing findings. In a report issued late last month, the organization found that antimicrobial resistance in bacteria (the main focus of the report), fungi, viruses and parasites is an increasingly serious threat in every part of the world. “A problem so serious that it threatens the achievements of modern medicine,” the organization said. “A post-antibiotic era, in which common infections and minor injuries can kill, far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.” 

        The growth of antibiotic-resistant pathogens means that in ever more cases, standard treatments no longer work, infections are harder or impossible to control, the risk of spreading infections to others is increased, and illnesses and hospital stays are prolonged. All of these drive up the costs of illnesses and the risk of death. The survey sought to determine the scope of the problem by asking countries to submit their most recent surveillance data (114 did so). Unfortunately, the data was glaringly incomplete because few countries track and monitor antibiotic resistance comprehensively, and there is no standard methodology for doing so.

        Still, it is clear that major resistance problems have already developed, both for antibiotics that are used routinely and for those deemed “last resort” treatments to cure people when all else has failed. Carbapenem antibiotics, a class of drugs used as a last resort to treat life-threatening infections caused by a common intestinal bacterium, have failed to work in more than half the people treated in some countries. The bacterium is a major cause of hospital-acquired infections such as pneumonia, bloodstream infections, and infections in newborns and intensive-care patients. Similarly, the failure of a last-resort treatment for gonorrhoea has been confirmed in 10 countries, including many with advanced health care systems, such as Australia, Canada, France, Sweden and Britain. And resistance to a class of antibiotics that is routinely used to treat urinary tract infections caused by E. coli is widespread; in some countries the drugs are now ineffective in more than half of the patients treated. This sobering report is intended to kick-start a global campaign to develop tools and standards to track drug resistance, measure its health and economic impact, and design solutions.

       The most urgent need is to minimize the overuse of antibiotics in medicine and agriculture, which accelerates the development of resistant strains. In the United States, the Food and Drug Administration (FDA) has issued voluntary guidelines calling on drug companies, animal producers and veterinarians to stop indiscriminately using antibiotics that are important for treating humans on livestock; the drug companies have said they will comply. But the agency, shortsightedly, has appealed a court order requiring it to ban the use of penicillin and two forms of tetracycline by animal producers to promote growth unless they provide proof that it will not promote drug-resistant microbes.

       The pharmaceutical industry needs to be encouraged to develop new antibiotics to supplement those that are losing their effectiveness. The Royal Pharmaceutical Society, which represents pharmacists in Britain, called this month for stronger financial incentives. It said that no new class of antibiotics has been discovered since 1987, largely because the financial returns for finding new classes of antibiotics are too low. Unlike lucrative drugs to treat chronic diseases like cancer and cardiovascular ailments, antibiotics are typically taken for a short period of time, and any new drug is apt to be used sparingly and held in reserve to treat patients resistant to existing drugs. Antibiotics have transformed medicine and saved countless lives over the past seven decades. Now, rampant overuse and the lack of new drugs in the pipeline threaten to undermine their effectiveness.

    (www.nytimes.com. Adaptado.)

    According to the fourth paragraph of the text, the Food and Drug Administration
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    The Rise of Antibiotic Resistance 

    By The Editorial Board

    May 10, 2014


        The World Health Organization has surveyed the growth of antibiotic-resistant germs around the world – the first such survey it has ever conducted – and come up with disturbing findings. In a report issued late last month, the organization found that antimicrobial resistance in bacteria (the main focus of the report), fungi, viruses and parasites is an increasingly serious threat in every part of the world. “A problem so serious that it threatens the achievements of modern medicine,” the organization said. “A post-antibiotic era, in which common infections and minor injuries can kill, far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.” 

        The growth of antibiotic-resistant pathogens means that in ever more cases, standard treatments no longer work, infections are harder or impossible to control, the risk of spreading infections to others is increased, and illnesses and hospital stays are prolonged. All of these drive up the costs of illnesses and the risk of death. The survey sought to determine the scope of the problem by asking countries to submit their most recent surveillance data (114 did so). Unfortunately, the data was glaringly incomplete because few countries track and monitor antibiotic resistance comprehensively, and there is no standard methodology for doing so.

        Still, it is clear that major resistance problems have already developed, both for antibiotics that are used routinely and for those deemed “last resort” treatments to cure people when all else has failed. Carbapenem antibiotics, a class of drugs used as a last resort to treat life-threatening infections caused by a common intestinal bacterium, have failed to work in more than half the people treated in some countries. The bacterium is a major cause of hospital-acquired infections such as pneumonia, bloodstream infections, and infections in newborns and intensive-care patients. Similarly, the failure of a last-resort treatment for gonorrhoea has been confirmed in 10 countries, including many with advanced health care systems, such as Australia, Canada, France, Sweden and Britain. And resistance to a class of antibiotics that is routinely used to treat urinary tract infections caused by E. coli is widespread; in some countries the drugs are now ineffective in more than half of the patients treated. This sobering report is intended to kick-start a global campaign to develop tools and standards to track drug resistance, measure its health and economic impact, and design solutions.

       The most urgent need is to minimize the overuse of antibiotics in medicine and agriculture, which accelerates the development of resistant strains. In the United States, the Food and Drug Administration (FDA) has issued voluntary guidelines calling on drug companies, animal producers and veterinarians to stop indiscriminately using antibiotics that are important for treating humans on livestock; the drug companies have said they will comply. But the agency, shortsightedly, has appealed a court order requiring it to ban the use of penicillin and two forms of tetracycline by animal producers to promote growth unless they provide proof that it will not promote drug-resistant microbes.

       The pharmaceutical industry needs to be encouraged to develop new antibiotics to supplement those that are losing their effectiveness. The Royal Pharmaceutical Society, which represents pharmacists in Britain, called this month for stronger financial incentives. It said that no new class of antibiotics has been discovered since 1987, largely because the financial returns for finding new classes of antibiotics are too low. Unlike lucrative drugs to treat chronic diseases like cancer and cardiovascular ailments, antibiotics are typically taken for a short period of time, and any new drug is apt to be used sparingly and held in reserve to treat patients resistant to existing drugs. Antibiotics have transformed medicine and saved countless lives over the past seven decades. Now, rampant overuse and the lack of new drugs in the pipeline threaten to undermine their effectiveness.

    (www.nytimes.com. Adaptado.)

    No trecho do quarto parágrafo “has appealed a court order requiring it to ban the use of penicillin”, o termo em destaque se refere a
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